【简介】博士后招聘网整理分享“2018年柏林夏里特医学院博士后招聘（代谢与系统生物化学）”，浏览查询更多博士后招聘计划请访问博士后招聘网。

The Charité – Universitätsmedizin Berlin is Germany's largest and most research intensive Medical Faculty, known, for instance, from the award of eleven Nobel Prizes.

We are looking for an enthusiastic postdoctoral scientist to join Prof. Markus Ralser’s laboratory at Institute for Biochemistry of the Charité – Universitätsmedizin Berlin. Ralser’s laboratory is world-renowned for its studies that understanding how cellular metabolism, the network of biochemical reactions in the cell, is regulated, how it evolved and how it maintains functional integrity in the ever changing environment the cell is exposed to. This research addresses fundamental problems in the life sciences, where knowledge about cellular metabolic systems is required to develop new therapeutics and to understand the molecular basis of disease.

Your area of responsiblity

We are currently generating a large multi-omic network, in which the metabolic phenotype of a yeast cell will be linked to all of its genes. We have created a library of ~5,000 gene deletions strains with a functional metabolism, have recorded metabolomes for all of them, and are in the process of acquiring a proteome for them. We currently aim to expand this endeavor by recording single-cell transcriptomes and lipidomes, and aim to expand our computational efforts to explain phenotype from the molecular layers. The project should pave the way to develop functionally predictors out of human omic data, for instance genomes or proteomes, for disease progression. The post offered is hence attractive both for computational and experimental biologists.

Further reading:

Muelleder et al, Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell. 2016. 167(2):553-565.e12. 

Alam et al, The metabolic background is a global player in Saccharomyces gene expression epistasis. Nature Microbiology. 2016. 2 (1), 15030.

Haas et al, Designing and interpreting ‘multi-omic’ experiments that may change our understanding of biology. Current Opinion in Systems Biology. 2017. 6:37-45.

The activity serves the own further scientific qualification.

Your profile

PhD, or Research Doctorate, in the basic sciences

Productivity documented in published research articles or patents;

If computational, experience in the handling of large datasets, and respective programming and statistical skills

If experimental, experience in the conduction of systematic, perhaps large-scale, experiments

Desirable are experimental skills in Microbiology and Biochemistry

Ref. No

CC02-10.18

Start

October 1st, 2018

Length of employment

limited until September 30th, 2021 (option on extension)

Working time

39 hours per week

Salary

E13 TVöD VKA-K 

Employees are grouped into pay scales according to their qualifications and personal requirements. You can find our collective bargaining agreements (Tarifverträge) here: https://www.charite.de/en/careers

Contact Person

Prof. Markus Ralser 

e-mail: markus.ralser@charite.de

Website: https://ralser-sysbiol.crick.ac.uk/

Tel: +49 (0)30-450 528142 (Office)…

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。