【简介】博士后招聘网整理分享“2018年弗朗西斯·克里克研究所博士后职位招聘（FAM83-蛋白质家族的功能相关研究）”，浏览查询更多博士后招聘计划请访问博士后招聘网。

Postdoctoral Training Fellow

The Francis Crick Institute

Location:	London
Salary:	Competitive with benefits, subject to skills and experience
Hours:	Full Time
Contract Type:	Fixed-Term/Contract

Placed On:	15th August 2018
Closes:	13th September 2018
Job Ref:	8384

Contract: Fixed-term (3 years), full time

Short summary

A postdoctoral research post in the laboratory of Jim Smith is now available. We are looking for a highly motivated researcher to use Xenopus and other vertebrate models to study the function of the FAM83 family of proteins, in a project involving collaboration with Gopal Sapkota (Dundee). The work will focus particularly on the role of FAM83 family members in Wnt signalling; the ways in which FAM83 family members might behave as scaffold proteins; and the role of FAM83G in ciliogenesis (in both Xenopus and in mammalian cells). Other experiments will involve analysis of proteins that interact with FAM83 family members and the roles of FAM83 family members in disease. There will also be the opportunity to contribute to analyses of the very early stages of Xenopus development.

The successful applicant will use a wide range of techniques including (but not limited to) experimental embryology, next-generation sequencing (ChIP-seq, RNA-seq, ATAC-seq, ini-seq, and so on), bioinformatics, time-lapse micrography, and cell biology.

Project scope

The Developmental Biology Laboratory at the Francis Crick Institute studies the development of various vertebrate species, including Xenopus, zebrafish and mouse, to find out how the different types of cells in an embryo form in the right place at the right time. The group is small and collegial, and it collaborates widely with other research groups both in the Crick and elsewhere. The team has recently contributed to our understanding of the mid-blastula transition in Xenopus; it has identified the nature of off-target effects in the use of anti-sense morpholino oligonucleotides; it has shed light on the genetic regulatory networks that underlie mesoderm formation; and it has collaborated with Gopal Sapkota in Dundee to understand the many functions of the FAM83 family.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

The closing date for applications is 13 September 2018 at 23:30.

All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

请您在邮件申请时在标题注明信息来自：博士后招聘网-boshihoujob.com，电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。

声明：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。邮箱：boshihoujob@163.com。