美国加州大学旧金山分校招聘癌症生物学方向博士后
信息来源:未知 | 作者:admin | 时间:2016-07-13 16:06
【简介】博士后招聘网整理分享“美国加州大学旧金山分校招聘癌症生物学方向博士后”,浏览查询更多博士后招聘计划请访问博士后招聘网。
Our group is interested in comparative analyses of normal lymphocyte development and malignant transformation towards leukemia. We cover research areas with relevance to both Immunology and Hematology/Cancer Biology. Our research involves experiments with primary human leukemia cells, leukemia and stem cell transplantation models, mouse genetics, classical molecular and cell biology, a strong emphasis on signal transduction and large-scale data analysis and computational biology.
Methods/Techniques:
Flow cytometry, mass spectrometry/quantitative phospho-profiling, CyTOF, mouse genetics, bone marrow transplantation assays, retroviral gene delivery, whole exome sequencing andRNA-seq-analysis of clonal evolution of leukemia, pre-clinical drug testing in xenotransplantation models.
Examples of our recent work:
1. Shojaee S et al. Erk negative feedback control enables pre-B cell transformation and represents a therapeutic target in acute lymphoblastic leukemia. Cancer Cell. 2015; 28:114-128.
http://www.sciencedirect.com/science/article/pii/S1535610815001841/pdfft?md5=2eda98a972e36350efc3d6a2962930ce&pid=1-s2.0-S1535610815001841-main.pdf
2. Swaminathan S. et al. Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. Nature Immunol. 2015;16: 766-774.
http://www.nature.com/ni/journal/v16/n7/pdf/ni.3160.pdf
3. Chen Z. et al., Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015; 521:357-361.
http://www.nature.com/nature/journal/v521/n7552/pdf/nature14231.pdf
4. Geng H. et al. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. Cancer Cell. 2015; 27: 409-425.
http://www.sciencedirect.com/science/article/pii/S1535610815000537/pdfft?md5=de304267b4862c5b82dc8d1f81d44f7a&pid=1-s2.0-S1535610815000537-main.pdf
5. Shojaee S et al., PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nature Med. 2016; 22: 379-387
http://www.nature.com/nm/journal/v22/n4/pdf/nm.4062.pdf
Qualifications:
Genuine enthusiasm for science, willingness to think beyond established concepts and to try and learn new experimental and analysis tools. The lab takes a team science approach, so being a nice person and is important as well.
Your application should include in one single PDF:
(1) brief motivation statement, (2) CV and (3) coordinates of three scientific mentors (references).
Contact information:
Markus Müschen, MD-PhD
Markus.muschen@ucsf.edu
http://cancer.ucsf.edu/people/profiles/muschen_markus.3312 |
|
|
|
Contact: |
Markus Muschen, MD-PhD
University of California San Francisco
513 Parnassus Ave
San Francisco, CA 94143
United States
Email: markus.muschen@ucsf.edu |
|
请您在邮件申请时在标题注明信息来自:博士后招聘网-boshihoujob.com,电话咨询时说明从博士后招聘网(www.boshihoujob.com)看到的博士后招聘信息。
声明:凡本网注明“来源:XXX”的文/图等稿件,本网转载出于传递更多信息及方便产业探讨之目的,并不意味着本站赞同其观点或证实其内容的真实性,文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用,须保留本网站注明的“来源”,并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜,请与我们联系。邮箱:boshihoujob@163.com。