美国H.Lee莫菲特癌症中心2024年招聘博士后职位（黑色素瘤中的RNA修饰）

Postdoctoral Fellow – RNA Modifications in Melanoma

H. Lee Moffitt Cancer Center

Job Description

A fully funded postdoctoral position is available in the laboratory of Florian A. Karreth, PhD in the Department of Molecular Oncology at Moffitt Cancer Center in Tampa, FL. The Karreth lab studies the molecular and genetic mechanisms promoting melanoma progression, metastasis, and drug resistance. We are recruiting a postdoctoral fellow to work on glyco-RNA at the intersection of glycobiology and RNA biology in the context of melanoma. This project is funded by the Department of Defense and will involve the characterization of glyco-RNA formation and function and their role in mediating melanoma progression and metastasis by affecting interactions with the tumor microenvironment and immune system. The successful candidate will use a variety of cell biological, molecular biological, and biochemical methods, and generate innovative genetically engineered mouse models to better understand glyco-RNAs in the context of spontaneous melanoma development. The ultimate goal is to identify vulnerabilities and opportunities for therapeutic targeting, and novel therapeutic strategies will be tested in vitro and in novel mouse models.

For more information about the Karreth Lab, please visit: http://labpages2.moffitt.org/karreth/

Position Highlights:

· Fully funded postdoctoral position on dissecting the functions of novel glyco-RNAs in melanoma.

· Work with sophisticated mouse models and other cutting-edge technologies.

· Unique access to patient samples and opportunity to translate findings into clinical trials.

· Outstanding mentorship from expert faculty with wide-ranging funded research programs including T32 Training Grants.

· You will be encouraged and supported to apply for training grants.

· Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.

The Ideal Candidate:

· Background in Molecular Biology, Cancer Biology, Biochemistry, Genetics, or similar field.

· Expertise in RNA biology or glycobiology is required. Experience with cancer mouse models or melanoma biology is desirable but not required.

· Strong work ethic.

· Motivated to work in a team and passionate about cancer research.

Responsibilities:

· Independently design and execute experiments.

· Assist with training junior lab members including undergraduate and graduate students.

· Present results in lab meeting, internal progress meetings, and international conferences.

· Assist with manuscript and grant writing.

Credentials and Qualifications:

· PhD, MD, or MD/PhD in Molecular Biology, Cancer Biology, Biochemistry, Genetics, or similar field .

· Evidence of recent scientific productivity in the form of first-author publication(s).

How to Apply: Interested applicants should send a cover letter, a current CV, and contact information for three references to Dr. Florian Karreth (florian.karreth@moffitt.org).

Moffitt Cancer Center and Research Institute is proud to be Florida’s only National Cancer Institute-designated Comprehensive Cancer Center located in Tampa. We strive to be the leader in understanding the complexity of cancer through team science and applying those insights for human benefits. Every Team Member of Moffitt focuses on our lasting commitment to our mission: To contribute to the prevention and cure of cancer.

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