一、课题组简介

陶生策教授团队长期深耕系统生物学与高通量生物学，率先建立了蛋白质芯片平台，原创开发了临近标记技术SPIDER，并在药物靶蛋白发现与作用机制研究方向持续取得突破，相关成果已发表于多篇国际期刊。现因科研工作需要，诚邀1–2名优秀青年博士加入，共同探索环肽药物新天地。

二、招聘岗位：博士后研究员（1-2名）

三、研究方向：

环肽药物的筛选、改造与功能解析

基于mRNAdisplay/phagedisplay搭建环肽筛选新平台

开发基因编码与非天然氨基酸介导的环肽合成策略

对获选分子进行结构优化及体内外功能验证

四、岗位要求：

已获或即将获得生物学、医学、化学生物学等相关领域博士学位；

具备环肽设计‑合成或mRNAdisplay经验者优先；

具有扎实的分子生物学、细胞与动物实验操作基础；

以第一作者身份在国际期刊发表过高水平论文，药物作用机制方向优先；

英文听说读写流利，能独立撰写科研论文；

热爱科研，责任心强，具备良好的团队协作与沟通能力。

五、薪酬与支持：

按照上海交通大学博士后管理规定执行；

课题组将依据科研贡献提供具有竞争力的绩效奖励；

提供一流科研平台与国际合作机会，支持个人职业发展。

六、申请方式：

请将个人简历（含代表性论文）及求职信发送至：taosc@sjtu.edu.cn

邮件主题请注明：“博士后申请+姓名+博士后招聘网”。

初审通过者将尽快通知面试事宜。

七、实验室主页：https://taolab.sjtu.edu.cn

我们诚邀立志于高通量药物研究的青年才俊加盟，共同推动前沿科学进步！

Postdoctoral Research Opportunities

Professor Sheng‑ce Tao Laboratory, Institute of Systems Biomedicine, Shanghai Jiao Tong University

About the Lab

The Tao Lab pioneers large‑scale and systems‑level approaches to biology. We established one of the first comprehensive protein microarray platforms, invented the proximity‑labeling technology SPIDER, and continue to develop cutting‑edge methods for target identification and mechanism‑of‑action studies. Our recent work on drug‑target discovery has been published in leading international journals. To expand these efforts, we invite 1–2 talented postdoctoral researchers to join our multidisciplinary team.

Position

· Postdoctoral Researcher (Full‑time, 1–2 openings)

Research Focus

· Cyclic‑peptide therapeutics: discovery, optimization, and functional characterization

Construct novel mRNA display / phage display platforms for cyclic‑peptide screening

Develop gene‑encoded and non‑canonical amino‑acid‑based synthesis strategies

Optimize lead peptides and evaluate their biological activity in vitro and in vivo

Candidate Qualifications

1.Ph.D. (awarded or expected soon) in chemical biology, molecular biology, biomedical sciences, or related fields

2.Hands‑on experience in cyclic‑peptide design/synthesis or mRNA display is highly desirable

3.Solid skills in molecular biology, cell culture, and animal experimentation

4.Proven publication record as first author in peer‑reviewed international journals (mechanistic drug studies preferred)

5.Excellent English communication skills, with the ability to write scientific manuscripts independently

6.Strong commitment to research, a sense of responsibility, and effective teamwork abilities

Compensation & Support

· Salary and benefits are in accordance with Shanghai Jiao Tong University’s postdoctoral regulations

·Competitive performance‑based bonuses commensurate with research contributions

· Access to state‑of‑the‑art facilities, professional mentoring, and international collaboration networks to foster career development

Application Procedure

Please email the following materials to taosc@sjtu.edu.cn::

· Curriculum vitae (including a list of representative publications)

· Cover letter outlining research interests and career goals

Email subject line: “Postdoc Application – [Your Name]”

Shortlisted candidates will be contacted promptly for an interview.

Lab Website

https://taolab.sjtu.edu.cn

We warmly welcome motivated young scientists passionate about high‑throughput drug research to join us and advance frontier science together!

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原文出处：

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