深圳医学科学院许献忠（Shawn Xu）感知生物学课题组现面向社会公开招聘副研究员/助理研究员、博士后、科研助理、实验室管理员，并招收访问学生。

The Shawn Xu Sensory Biology research group at the Shenzhen Medical Academy of Sciences (SMART) is now recruiting Associate Investigators/Assistant Investigators, Postdoctoral Fellows, Research Assistants, and Laboratory Managers, and welcomes Visiting Students.

一、 课题组简介丨Group Introduction

生物感知包括两大类：一类是对外部环境的感受，即外感受；另一类是对身体内部状态的整体感受，即内感受。外感受涵盖对外界温度、光线、声音、气味、压力等信号的感知，是我们连接世界、适应环境并做出行为决策的关键生理基础，帮助我们回答一个最基本的问题：“我身处何处？环境如何？”内感受则不仅包括内脏痛等感觉，还涉及呼吸频率、体温、口渴、饥饿、疲劳等身体状态，是我们感知自我、产生情绪和维持生命的重要生理过程，帮助我们回答另一个基本问题：“我自身感觉怎么样？”此外，生物感知还对代谢、衰老等关键生命过程发挥决定性调控作用。生物感知功能异常，既是耳鸣、耳聋、色盲、视力损伤等经典感觉障碍的直接病因，也作为核心症状广泛出现在神经退行性疾病、慢性疼痛、糖尿病、心血管疾病等多种重大疾病中。因此，从分子—细胞—环路多层次阐明生物感知的过程与分子机制，对于发现新型疾病治疗靶点、解析疾病机理具有重要意义。

The Xu lab focuses on sensory biology, aiming to understand how we sense both the external environment (exteroception) and internal world (interoception) using C. elegans and mouse models. Exteroception allows us to sense external cues such as temperature, light, sound, odorants, tastants, and touch, serving as a key physiological foundation for connecting us to the external world, adapting to our surroundings, and guiding behavioral decisions. Interoception, on the other hand, not only underlies visceral pain and related sensations but also regulates physiological states such as respiratory rate, core body temperature, thirst, hunger, and fatigue. It is a vital physiological process that controls self-perception, emotional experience, and the maintenance of life. Furthermore, exteroception and interoception play key roles in regulating other vital physiological processes such as metabolism and aging. Dysfunction in exteroception/interoception is not only a direct cause of classical sensory disorders such as tinnitus, deafness, color blindness, and visual impairment, but also represents a core symptom widely associated with various human diseases, including neurodegenerative diseases, chronic pain, diabetes, and cardiovascular diseases. As such, elucidating the molecular, cellular and circuit mechanisms of exteroception and interoception is of great significance for developing novel therapeutics.

感知生物学课题组聚焦于生物感知的前沿研究，课题组负责人许献忠（Shawn Xu）教授是感知生物学领域的知名学者，带领课题组以线虫(C. elegans)和小鼠为研究模型，深入探索了动物感知温度、压力、光、声音、气味、味道等感觉信号的分子细胞机制，首次证实秀丽隐杆线虫除触觉、味觉和嗅觉外，还具备视觉、听觉、本体觉，即其具备全部六种主要感觉模态，充分确立了线虫作为研究感知生物学理想遗传模型的地位；在此基础上，课题组通过经典遗传学手段在线虫中筛选和鉴定出多个新型感知受体，比如新型光感受器LITE-1、新型冷感受体GLR-3/GluK2、新型碱性感受体TMC-1/mTMC3、机械敏感性离子通道TRP-4/TRPN1，并解析了其信号传导机制；在小鼠模型中证实了多个受体分子及信号通路的功能保守性。此外，他们还深入揭示了多条关键神经环路处理感觉信号以调节动物运动行为和药物依赖性的具体作用及机制。课题组的研究还表明，除了影响大脑功能和行为之外，温度和气味等感觉信号也能够调节衰老和寿命等其他生理过程，并阐明了其背后的遗传与神经机制。这些研究拓展并加深了我们对感觉信号调控大脑功能、行为以及衰老过程的理解。

Professor Shawn Xu is a leading scientist in sensory biology. Using C. elegans and mice as models, the Xu lab has made a series of contributions to our understanding of how animals detect and process sensory signals such as temperature, light, sound, touch, smell, and taste. The group was the first to demonstrate that, in addition to touch, taste, and smell, the nematode C. elegans also possesses the senses of light, airborne sound, and proprioception. These discoveries established that C. elegans has all six primary sensory modalities, fully establishing this animal as a powerful genetic model for the study of sensory biology. Building on these foundational discoveries, the Xu lab has identified multiple novel sensory receptors, including the photoreceptor LITE-1, the cold receptor GLR-3/GluK2, the alkaline receptor TMC-1/mTMC3, and the mechanosensitive channel TRP-4/TRPN1, among others. Importantly, they have demonstrated the functional conservation of some of these sensory receptors and their downstream signaling pathways using mouse models. Furthermore, they have characterized how neural circuits process sensory signals to regulate behavior and drug dependence. Moreover, their work has revealed that beyond brain function and behavior, sensory signals such as temperature and smell also regulate other vital physiological processes such as aging and longevity, and has elucidated the underlying genetic and neural mechanisms. These studies have expanded and deepened our understanding of how sensory cues regulate brain function, behavior, and aging.

许献忠（Shawn Xu）博士曾任美国密歇根大学讲席教授，2026年全职加入深圳医学科学院，担任生物构造与互作研究所资深研究员。他长期深耕生物感知领域，以通讯作者在Cell、Nature、Neuron、Nature Neuroscience、Cell Metabolism、Nature Aging、Developmental Cell等国际顶级期刊上发表多篇原创研究成果，这些开创性工作填补了该领域的多项研究空白，奠定了线虫感知生物学的研究基础。未来，课题组将继续依托线虫(C. elegans)和小鼠模型，重点推进以下三方面工作：一是筛选新型外感受与内感受感知受体，解析其信号传导机制与结构功能关系；二是从分子、细胞和环路水平解码感觉信号调控脑功能、行为、代谢、衰老等生理过程的作用机制；三是靶向感知受体开发与筛选小分子创新药物，助力前沿科学发现向突破性疗法的有效转化。

Dr. Xu previously held Bernard W. Agranoff Collegiate Professorship at the University of Michigan. In 2026, Dr. Xu joined the Institute of Bio-Architecture and Bio-Interactions of SMART as a senior investigator. Dr. Xu has published many research articles in high profile journals such as Cell, Nature, Neuron, Nature Neuroscience, Cell Metabolism, Nature Aging, and Developmental Cell. Moving forward, Professor Xu’s group will continue to leverage C. elegans and mouse models to: i) identify novel sensory receptors detecting various exteroceptive and interoceptive signals and characterize their physiological functions and structure-function relationships; ii) elucidate how sensory signals regulate brain function, behavior, metabolism, and aging at the molecular, cellular, and circuit levels; and iii) screen for small molecules targeting sensory receptors to translate fundamental knowledge into novel therapeutics.

二、 岗位要求及福利待遇Positions and Benefits

(一) 副研究员/助理研究员（2名）Associate Investigator

Assistant Investigator (2 positions)

工作内容Job Responsibilities

1.在课题组长指导下独立开展科研工作；

Conduct independent research under the guidance of the PI.

2.独立或协助申请国内外的科研项目和论文撰写；

Independently or jointly apply for research grants and write research papers.

3.协助指导实验室博后、学生和科研助理的研究工作；

Assist in supervising postdocs, students, and research assistants.

4.协助实验室管理工作。

Support laboratory management.

应聘条件Requirements

1.具有国内外一流研究机构博士学位和博士后研究经历；

Possess a Ph.D. degree and postdoctoral research experience from leading research institutions in China or abroad.

2.以第一作者或通讯作者发表过多篇高水平科研论文；

Have published multiple high-impact scientific papers as the first author or corresponding author.

3.具有神经生物学、生理学、遗传学、生物化学或细胞生物学等专业背景，基础知识扎实；

Have a solid academic background in neurobiology, physiology, genetics, biochemistry, or cell biology.

4.具有良好沟通能力和团队协作能力、优良学术道德、严谨科学态度、强烈探索兴趣，勤奋，追求卓越，具有独立开展科研工作的能力；

Possess excellent communication and teamwork skills, high academic integrity, a rigorous scientific attitude, a strong passion for discovery, diligence, a commitment to excellence, and the ability to conduct independent research.

5.能熟练以英语作为工作语言进行口头和书面学术交流。

Be proficient in using English as a working language for both oral and written academic communication.

(二) 博士后（5-6名）Postdoctoral Fellow (5-6 positions)

工作内容Job Responsibilities

1.在课题组长指导下开展独立或合作科研工作；

Conduct independent or collaborative research under the guidance of the PI.

2.协助申请各类科研项目。

Assist in applying for research grants.

应聘条件

Requirements

1.已获得博士学位，以第一作者在本专业领域发表或即将发表研究论文至少一篇，具有独立开展科研工作的能力；

Have obtained a Ph.D. degree, with at least one research paper published or about to be published as the first author in a relevant field, and possess the ability to conduct independent research.

2.具有神经生物学、生理学、遗传学、生物化学或细胞生物学等专业背景，基础知识扎实；

Have a solid academic background in neurobiology, physiology, genetics, biochemistry, or cell biology.

3.具有强烈进取心和责任感，良好的团队协作意识，勤奋，追求卓越，具有独立开展科研工作的能力；

Be highly motivated and responsible, with strong teamwork spirit, diligence, a commitment to excellence, and the ability to conduct independent research.

4.具有良好的英文科技文献阅读和写作能力。

Have a good command of English for reading and writing scientific literature.

(三) 研究助理-I（线虫C. elegans方向 2名）

Research Assistant I – with C. elegans experience (2 positions)

工作内容

Job Responsibilities

1.协助实验室建设及管理；

Assist in laboratory management.

2.协助副研究员/助理研究员、博士后、博士生的科研工作；

Assist Associate/Assistant Investigators, Postdoctoral Fellows, and PhD students in research work.

3.可在课题组长指导下相对独立地开展科研工作；

Conduct relatively independent research under the supervision of the PI.

4.协助完成实验室安排的其他工作。

Assist with other tasks assigned by the laboratory.

应聘条件

Requirements

1.有线虫C. elegans科研经历；

Applicants should have research experience in C. elegans.

2.硕士学历优先；

Master’s degree preferred.

3.有责任心，操作能力强，有良好的协作和沟通能力；

Be responsible, skilled in laboratory operations, and possess strong collaboration and communication abilities.

4.有较好的英文阅读和写作能力。

Have good English reading and writing proficiency

(四) 研究助理-II（小鼠及其他方向 2名）

Research Assistant II – with experience using mouse and other models (2 positions)

工作内容

Job Responsibilities

1.协助实验室建设及管理；

Assist in laboratory management.

2.协助副研究员/助理研究员、博士后、博士生的科研工作；

Assist Associate/Assistant Investigators, Postdoctoral Fellows, and PhD students in research work.

3.可在课题组长指导下相对独立地开展科研工作；

Conduct relatively independent research under the supervision of the PI.

4.协助完成实验室安排的其他工作。

Assist with other tasks assigned by the laboratory.

应聘条件

Requirements

1.有小鼠操作经验或细胞和分子生物学实验技能的申请者优先；

Applicants with experience in mouse handling or cell and molecular biology techniques are preferred.

2.硕士学历优先；

Master’s degree preferred.

3.有责任心，操作能力强，有良好的协作和沟通能力；

Be responsible, skilled in laboratory operations, and possess strong collaboration and communication abilities.

4.有较好的英文阅读和写作能力。

Have good English reading and writing proficiency.

(五) 实验室管理员（1名）

Laboratory Manager (1 position)

工作内容

Job Responsibilities

1.负责实验室日常运行管理；

Responsible for the daily operation and management of the laboratory.

2.实验室设备、试剂、耗材以及研究资源的订购、维护和管理；

Handle procurement, maintenance, and management of laboratory equipment, reagents, consumables, and research resources.

3.人员管理，包括接待来访的学者与学生，新进组人员培训，协调设备的使用与共享等；

Manage personnel matters, including hosting visiting scholars and students, onboarding and training new members, and coordinating equipment use and sharing.

4.协助实验动物管理。

Assist in the management of laboratory animals.

应聘条件

Requirements

1.本科及以上学历，有长期工作意愿者优先；

Hold a bachelor’s degree or above; candidates with a long-term career plan are preferred.

2.具有独立和高效的工作能力，具有良好的职业道德和团队合作精神，有责任心，善于沟通；

Be capable of working independently and efficiently, with strong professional ethics, teamwork spirit, responsibility, and good communication skills.

3.有较好的英语读写能力；

Have good English reading and writing skills.

4.有实验室管理经验、线虫、小鼠操作经验或细胞和分子生物学实验技能的申请者优先。

Applicants with laboratory management experience, C. elegans or mouse handling experience, or expertise in cell and molecular biology techniques are preferred.

(六) 访问学生（若干）

Visiting Students (Multiple positions)

课题组欢迎神经生物学、遗传学、生物化学、分子/细胞生物学、免疫学、生物信息学、统计等相关专业领域本科高年级学生前来访问学习。

Senior undergraduate students majoring in neurobiology, genetics, biochemistry, molecular/cell biology, immunology, bioinformatics, statistics, or related fields are welcome to join the group as visiting students.

三、 福利待遇Benefits

1.按照本单位薪酬体系，提供具有市场竞争力的薪酬福利待遇，具体薪酬根据应聘者资历和成果面议；

Provide a competitive salary and benefits package based on the institute’s compensation system, with specific pay determined according to the candidate’s qualifications and achievements;

2.享受国家规定的相关福利，享受带薪年休假、员工体检等；

Enjoy statutory benefits, paid annual leave, regular health check-ups, and other employee welfare programs;

3.提供良好科研训练和科研环境；

Provide excellent research training and a supportive research environment;

4.若符合相关规定，可协助申请相关人才补助及相关配套待遇；

For qualified candidates, assistance will be provided in applying for relevant talent subsidies and supporting programs;

5.对于科研助理和访问学生，工作表现优秀者，根据本人意愿，课题组可推荐申请研究生项目；

For Research Assistants and Visiting Students with outstanding performance, the group may recommend them for graduate study programs upon request;

6.访问学生根据深圳医学科学院补贴标准提供生活补助。

Visiting Students will receive living allowances in accordance with the subsidy standards of the Shenzhen Medical Academy of Research and Translation.

四、 应聘材料及方式Application Materials and Process

应聘者请提供以下材料

Applicants should provide

1.完整的个人中文或英文简历，包括教育背景、科研经历及成果、主要科研技能、所获奖项、个人科研兴趣等；

A complete CV in Chinese or English, including educational background, research experience and achievements, key scientific skills, awards, and personal research interests;

2.请列出至少2位推荐人信息；

Please list the names of at least 2 referees.

3.其它能够说明科研和工作能力的材料。

Other materials that can demonstrate the applicant’s research and professional capabilities.

应聘者请将PDF版应聘材料作为附件发送至：elegant@smart.org.cn（邮件主题请注明“应聘岗位－姓名－专业”），待审核后会尽快安排时间面试。

Please send the application materials in PDF format to elegant@smart.org.cn (Email subject: “Position – Name – Major”). Qualified candidates will be notified for an interview.

应聘材料予以保密，待遇面议。

All applications will be kept confidential, and compensation is negotiable.

本招聘信息在职位未满前长期有效。

This recruitment notice remains open until all positions are filled.

更多最新博士后招聘信息请关注博士后招聘网微信公众号（ID：boshihoujob）

原文出处：

https://mp.weixin.qq.com/s/uHOAGLyC_5GIF72kd5flXA

来源：深圳医学科学院